Preclinical Toxicology Testing and IND application for a Novel Cholera Conjugate Vaccine

Key facts

Disease
Cholera
Start & end year
2020
2022
Known Financial Commitments (USD)
$595,871.29
Funder
Wellcome Trust
Principal Investigator
Dr. Julia Lynch
Research Location
South Korea
Lead Research Institution
International Vaccine Institute
Research Priority Alignment
N/A

Research Category
Vaccines research, development and implementation
Research Subcategory
Pre-clinical studies
Special Interest Tags
N/A
Study Type
Non-Clinical
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Not Applicable
Vulnerable Population
Not applicable
Occupations of Interest
Not applicable

Abstract

This grant award would ensure timely completion of a required toxicology study and development on an IND application in support of a first in human trial of this novel vaccine. This funding will advance a vaccine with the potential to enable sustained cholera control in high risk settings by inducing durable immunity across all ages including infants and toddlers at low cost, reducing cholera burden among the world's most vulnerable populations.