Predicting immunity against new pandemic viruses

  • Funded by Netherlands Organisation for Health Research and Development (ZonMW)
  • Total publications:0 publications

Grant number: 1.07101E+13

Grant search

Key facts

  • Disease

    COVID-19, Other
  • Start & end year

    2024
    2026
  • Known Financial Commitments (USD)

    $0
  • Funder

    Netherlands Organisation for Health Research and Development (ZonMW)
  • Principal Investigator

    dr. M van Boven
  • Research Location

    Netherlands
  • Lead Research Institution

    Universitair Medisch Centrum Utrecht
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

The impact of new pandemic viruses on public health is largely determined by the degree of existing cross immunity in the human population. Such cross immunity is caused by broad T and B cell immune response that determine the severity of the infection. During the recent SARS-COV-2 Pandemie, a prominent genetic association with asymptomatic infection was found, which is attributed to T-cell crusal immunity caused by the seasonal coronaviruses OC43 and HKU1.