EPIC TIGER - Epigenetic control of virus transmission by the Asian tiger mosquito

The Asian tiger mosquito Aedes Albopictus is an invasive species that transfers viruses such as the dengue and the Chikungunya virus. Before virustansmission takes place, these viruses must first multiply in the mosquito. Processes that prevent the virus reproduction in the MUG can therefore inhibit the virustansmission. However, the operating mechanisms of these types of processes are still largely unknown. In Epic Tiger, the researchers study whether epigenetic regulation plays a role in the defense against viruses in the mosquito. Proteins involved in epigenetic processes are best known as promising targets for cancer therapy in humans. As a result, an extensive selection of chemicals is available that inhibit these factors. In Epic Tiger, the scientists investigate whether these epigenetic inhibitors can prevent virus reproduction in the mosquito and can be used as a new strategy to block virus spreads by mosquitoes.