Pandemic Information to Support Rapid Response

Grant number: 101133191

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Key facts

  • Disease

    COVID-19, Other
  • Start & end year

    2024
    2028
  • Known Financial Commitments (USD)

    $7,738,706.63
  • Funder

    European Commission
  • Principal Investigator

    KIRKEBY Carsten
  • Research Location

    Denmark
  • Lead Research Institution

    KOBENHAVNS UNIVERSITET
  • Research Priority Alignment

    N/A
  • Research Category

    Animal and environmental research and research on diseases vectors

  • Research Subcategory

    Animal source and routes of transmission

  • Special Interest Tags

    Data Management and Data Sharing

  • Study Type

    Clinical

  • Clinical Trial Details

    Not applicable

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Emergency RespondersHealth PersonnelHospital personnelPhysicians

Abstract

In is clear that critical pandemic decisions need to link rapid, reliable testing with comprehensive modelling of potential impacts. Currently, Europe lacks a comprehensive One 1) A diagnostic point of care instrument (PANPOC) for rapid detection of respiratory RNA viruses with pandemic potential: Influenza A (human, avian and swine), influenza B and SARS-CoV-2 (the Target Viruses). PANPOC will be validated by testing animal, environmental and clinical samples (one health approach). 2) A prognostic AI-based platform (PANRISK) to predict the spread of the Target Viruses and contribute to public health by giving an alarm once an outbreak exceeds a given threshold. The platform is based on a pathogen genomic drifting model to predict the risk of animal pathogens drifting to become human pathogens and an epidemiological model to predict geographical and temporal outbreaks of zoonoses. The portable PANPOC equipment will be validated and demonstrated at end-users: hospitals, General practitioners, competent veterinary authorities, health authorities, border controls, airports, refugee camps, etc. The aim of PANRISK is a syndromic surveillance framework for diseases, for targeting directed surveillance in concentrated periods of time and areas. The advantage of the PANRISK model is targeted towards zoonotic diseases, with high precision data that allows high precision in the surveillance for trends. The contribution of social sciences and humanities (SSH) is integral to the project. An SSH partner will focus on social and health inequities in the pandemic preparedness and aims to provide indications for the implementation of the PPP to support the involvement of stakeholders as well as public trust. A policy development partner will align the projects output to the key policy development and implementation processes within the EU. A dissemination and communication partner will ensure efficient communication, dissemination and engagement of the stakeholders.