Glyco-protein arrays for functional virus surveillance

This ERC PoC project aims to establish the technical and commercial feasibility of our recently developed glycan-arrays in which we determined the minimal receptor for duck, chicken, and human influenza A viruses, respectively. We also determined structures vital for viruses as intermediate receptors on the avian-mammalian interface. With our experience in printing arrays, we also want to add proteinaceous receptors for coronaviruses. This mixed "glyco-protein" array will then be employed for functional surveillance of two virus families with significant pandemic threat. The ERC program "sugar-enable" has developed different glycan arrays that should be used in the real world to detect potential pandemic viruses as soon as possible, now making a substantial societal impact. In this project, we aim to conduct a technical and commercial feasibility study.