Return to homepagePandemic Pact

A novel regulator of interferon signalling

  • Funded by National Health and Medical Research Council (NHMRC)
  • Total publications:0 publications

Grant number: GA205197

Grant search

Key facts

  • Disease

    COVID-19

  • Start & end year

    2022
    2025

  • Known Financial Commitments (USD)

    $513,210.69

  • Funder

    National Health and Medical Research Council (NHMRC)

  • Principal Investigator

    N/A

  • Research Location

    Australia, United States of America

  • Lead Research Institution

    The Walter and Eliza Hall Institute of Medical Research

  • Research Priority Alignment

    N/A

  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Prognostic factors for disease severity

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Unspecified

  • Vulnerable Population

    Unspecified

  • Occupations of Interest

    Unspecified

Abstract

We have identified a new role for a protein called ARAP2 in regulating the immune response to infection. We have generated unique experimental models and have access to immune cells from 25 patients carrying ARAP2 mutations which will enable us to understand the role of ARAP2 in infectious diseases such as TB or Covid-19. This project offers the potential to identify and treat individuals at high risk of life-threatening infections.