Location! Location! Location! Geospatial control of memory B cell reactivation in vaccine-induced immunity

  • Funded by National Health and Medical Research Council (NHMRC)
  • Total publications:0 publications

Grant number: GA207594

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Key facts

  • Disease

    COVID-19
  • Start & end year

    2022
    2025
  • Known Financial Commitments (USD)

    $493,559.75
  • Funder

    National Health and Medical Research Council (NHMRC)
  • Principal Investigator

    N/A

  • Research Location

    Australia
  • Lead Research Institution

    University of New South Wales
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Vaccines are one of the great public health achievements in the modern era. However, vaccinology remains an empirical art and there is an urgent need to advance the science to realize its full potential, particularly in the face of pandemics such as COVID-19 and the emergence of virus variants that require booster injections. Here we propose to track the cell fate trajectories of memory B cells to determine the factors that are critical to generating a potent immune response to vaccination.