Location! Location! Location! Geospatial control of memory B cell reactivation in vaccine-induced immunity
- Funded by National Health and Medical Research Council (NHMRC)
- Total publications:0 publications
Grant number: GA207594
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Key facts
Disease
COVID-19Start & end year
20222025Known Financial Commitments (USD)
$493,559.75Funder
National Health and Medical Research Council (NHMRC)Research Location
AustraliaLead Research Institution
University of New South WalesResearch Priority Alignment
N/A
Research Category
Pathogen: natural history, transmission and diagnosticsResearch Subcategory
ImmunitySpecial Interest Tags
N/AStudy Type
Non-ClinicalClinical Trial Details
N/ABroad Policy Alignment
PendingAge Group
Not ApplicableVulnerable Population
Not applicableOccupations of Interest
Not applicable
Abstract
Vaccines are one of the great public health achievements in the modern era. However, vaccinology remains an empirical art and there is an urgent need to advance the science to realize its full potential, particularly in the face of pandemics such as COVID-19 and the emergence of virus variants that require booster injections. Here we propose to track the cell fate trajectories of memory B cells to determine the factors that are critical to generating a potent immune response to vaccination.