Reconstructing ancestral viruses to fight current and future flavivirus outbreaks

  • Funded by National Health and Medical Research Council (NHMRC)
  • Total publications:0 publications

Grant number: GA201495

Grant search

Key facts

  • Disease

    Unspecified
  • Start & end year

    2022
    2026
  • Known Financial Commitments (USD)

    $469,313.04
  • Funder

    National Health and Medical Research Council (NHMRC)
  • Principal Investigator

    N/A

  • Research Location

    Australia
  • Lead Research Institution

    The University of Queensland
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Diagnostics

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

I am a co-inventor of a powerful toolset combining advanced structural biology and rapid virus engineering that enables the investigation of flavivirus structure and immune response at the molecular level. This project integrates these approaches to resurrect ancient flaviviruses and explore the structural evolution of non-human primate flaviviruses, which will be used to understand viral evolution, improve outbreak preparedness and design safer and more effective vaccines.