Harnessing mucosal antibodies against respiratory viral infections

  • Funded by National Health and Medical Research Council (NHMRC)
  • Total publications:0 publications

Grant number: GA400326

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Key facts

  • Disease

    COVID-19, Unspecified
  • Start & end year

    2025
    2029
  • Known Financial Commitments (USD)

    $419,464.66
  • Funder

    National Health and Medical Research Council (NHMRC)
  • Principal Investigator

    N/A

  • Research Location

    Australia
  • Lead Research Institution

    University of Melbourne
  • Research Priority Alignment

    N/A
  • Research Category

    Pathogen: natural history, transmission and diagnostics

  • Research Subcategory

    Immunity

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Broad antibody protection could guard against recurring mucosal infections by coronavirus and influenza. However, the antibody types and targeted viral regions driving immunity, particularly at the mucosa, remain unknown. Here, we will identify 1) the antibody features best at protecting against coronavirus and influenza infection, 2) the vaccine platforms most suited to make these antibodies, and 3) if mucosal antibody therapeutics would work against active coronavirus and influenza infections.