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Accelerating messenger RNA (mRNA) therapeutics by cracking the epitranscriptomic code

  • Funded by National Health and Medical Research Council (NHMRC)
  • Total publications:0 publications

Grant number: GA279597

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2023
    2026

  • Known Financial Commitments (USD)

    $1,066,727.6

  • Funder

    National Health and Medical Research Council (NHMRC)

  • Principal Investigator

    N/A

  • Research Location

    Australia

  • Lead Research Institution

    Australian National University

  • Research Priority Alignment

    N/A

  • Research Category

    Therapeutics research, development and implementation

  • Research Subcategory

    Pre-clinical studies

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

The remarkable efficacy of SARS-CoV-2 vaccines based on messenger RNA (mRNA) has highlighted the extraordinary potential of mRNA technologies and has secured the promise of mRNA as a therapeutic modality for multiple diseases. This research project builds on a recent breakthrough from my research that enables an unprecedented characterisation of the chemical composition of individual mRNA molecules to uphold this promise and accelerate mRNA exploration and design for therapeutic development.