How the synergy between flavivirus protein and noncoding RNA defeats antiviral response
- Funded by National Health and Medical Research Council (NHMRC)
- Total publications:0 publications
Grant number: GA207587
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Key facts
Disease
UnspecifiedStart & end year
20222025Known Financial Commitments (USD)
$565,070.96Funder
National Health and Medical Research Council (NHMRC)Principal Investigator
N/A
Research Location
AustraliaLead Research Institution
The University of QueenslandResearch Priority Alignment
N/A
Research Category
Pathogen: natural history, transmission and diagnostics
Research Subcategory
Pathogen morphology, shedding & natural history
Special Interest Tags
N/A
Study Type
Non-Clinical
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Not Applicable
Vulnerable Population
Not applicable
Occupations of Interest
Not applicable
Abstract
Flaviviruses represent a persistent threat with a devastating impact on human health. They have sophisticated mechanisms to subvert and control human antiviral response. One of them is by producing a noncoding RNA. In this project we will obtain an understanding of how these RNAs determine the ability of flaviviruses to evade immune response and establish infection in humans. The outcome will advance our understanding of flavivirus pathogenesis and inform future design of novel antivirals.