Dissecting the mechanisms of flavivirus neuro-pathogenesis using the systems biology approach
- Funded by National Health and Medical Research Council (NHMRC)
- Total publications:0 publications
Grant number: GA276503
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Key facts
Disease
Zika virus disease, West Nile Virus Infection…Start & end year
20232025Known Financial Commitments (USD)
$654,781.44Funder
National Health and Medical Research Council (NHMRC)Principal Investigator
N/A
Research Location
AustraliaLead Research Institution
The University of QueenslandResearch Priority Alignment
N/A
Research Category
Pathogen: natural history, transmission and diagnostics
Research Subcategory
Pathogen morphology, shedding & natural history
Special Interest Tags
N/A
Study Type
Non-Clinical
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Not Applicable
Vulnerable Population
Not applicable
Occupations of Interest
Not applicable
Abstract
Flaviviruses are important pathogens that Include West Nile, Japanese encephalitis and Zika viruses. They can infect human brain causing severe neurological diseases. This project is aimed to identify the cells in the brain vulnerable to viral infection and elucidate the molecular processes affected by the viruses in the brain. This will explain why flaviviruses cause neurological disease and identify the molecules that can be targeted to prevent or mitigate infection in the brain.