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Defining the action of Vav proteins in dengue and zika virus infection

  • Funded by National Health and Medical Research Council (NHMRC)
  • Total publications:0 publications

Grant number: GA66013

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Key facts

  • Disease

    Zika virus disease, Dengue

  • Start & end year

    2020
    2022

  • Known Financial Commitments (USD)

    $324,344.19

  • Funder

    National Health and Medical Research Council (NHMRC)

  • Principal Investigator

    N/A

  • Research Location

    Australia

  • Lead Research Institution

    Flinders University

  • Research Priority Alignment

    N/A

  • Research Category

    Clinical characterisation and management

  • Research Subcategory

    Disease pathogenesis

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Dengue and zika viruses are important causes of human disease for which there are no effective treatments.This research will add significantly to our knowledge on the processes that occur to the body during disease leading to better management. We believe we have identified a pathway - involving the Vav proteins, that may influence a number of processes that cause disease. We will investigate how Vavs interact with dengue or zika and if we can manipulate this to benefit disease outcome.