Investigation of the structure of the influenza A virus genome and how it directs reassortment to generate novel strains
- Funded by National Health and Medical Research Council (NHMRC)
- Total publications:0 publications
Grant number: GA207610
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Key facts
Disease
UnspecifiedStart & end year
20222025Known Financial Commitments (USD)
$537,713.71Funder
National Health and Medical Research Council (NHMRC)Principal Investigator
N/A
Research Location
Australia, United KingdomLead Research Institution
University of MelbourneResearch Priority Alignment
N/A
Research Category
Pathogen: natural history, transmission and diagnostics
Research Subcategory
Pathogen morphology, shedding & natural history
Special Interest Tags
N/A
Study Type
Non-Clinical
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Not Applicable
Vulnerable Population
Not applicable
Occupations of Interest
Not applicable
Abstract
Pandemic influenza viruses acquire new properties through the swapping of gene segments known as reassortment. We will investigate the structure of the influenza A virus genome to dissect the molecular mechanism that enables specific genes to interact and be co-selected during reassortment. Our work will provide key insights into the probability of viruses with particular gene constellations emerging in the future, that will greatly benefit pandemic assessment and planning.