The Mental Health Impact of Childhood SARS-CoV-2
- Funded by National Health and Medical Research Council (NHMRC)
- Total publications:0 publications
Grant number: GA276595
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Key facts
Disease
COVID-19Start & end year
20232025Known Financial Commitments (USD)
$515,745.52Funder
National Health and Medical Research Council (NHMRC)Principal Investigator
N/A
Research Location
AustraliaLead Research Institution
RMIT UniversityResearch Priority Alignment
N/A
Research Category
Secondary impacts of disease, response & control measures
Research Subcategory
Indirect health impacts
Special Interest Tags
N/A
Study Type
Unspecified
Clinical Trial Details
N/A
Broad Policy Alignment
Pending
Age Group
Unspecified
Vulnerable Population
Unspecified
Occupations of Interest
Unspecified
Abstract
Children have key differences in ACE2, the receptor by which SARS-CoV-2 enters host cells, that may make them especially vulnerable to lasting brain damage. We show that a single ACE2 inhibition in juvenile rats leads to lasting anxiety- and depressive-like behaviour and associated brain changes. We hypothesize these effects will be worse the younger COVID-19 occurs. We will reveal the potential for COVID-19 to critically impact children, changing the approach to child health in this pandemic.