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Combatting dengue with emerging interventions

  • Funded by National Health and Medical Research Council (NHMRC)
  • Total publications:0 publications

Grant number: GA520879

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Key facts

  • Disease

    Dengue

  • Start & end year

    2026
    2028

  • Known Financial Commitments (USD)

    $575,147.53

  • Funder

    National Health and Medical Research Council (NHMRC)

  • Principal Investigator

    N/A

  • Research Location

    Australia

  • Lead Research Institution

    Burnet Institute

  • Research Priority Alignment

    N/A

  • Research Category

    Infection prevention and control

  • Research Subcategory

    Barriers, PPE, environmental, animal and vector control measures

  • Special Interest Tags

    N/A

  • Study Type

    Unspecified

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Cases of the mosquito-transmitted viral disease, dengue, are surging. No antiviral therapeutics are approved for use but two have demonstrated efficacy in Phase 2 clinical trials. We will define the molecular mechanism of one of these drugs, and determine its potential use in combination therapy. We will also test if mosquito-targeting interventions complement the use of antiviral therapeutics. Ultimately, these findings will aid in reducing the global mosquito-borne disease burden.