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Genomic surveillance of infectious diseases in wastewater 2024-2025

  • Funded by Federal Office of Public Health (FOPH)
  • Total publications:0 publications

Grant number: 54567

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Key facts

  • Disease

    COVID-19

  • Start & end year

    2024

  • Known Financial Commitments (USD)

    $859,550.48

  • Funder

    Federal Office of Public Health (FOPH)

  • Principal Investigator

    Born Rita

  • Research Location

    Switzerland

  • Lead Research Institution

    N/A

  • Research Priority Alignment

    N/A

  • Research Category

    Epidemiological studies

  • Research Subcategory

    Disease surveillance & mapping

  • Special Interest Tags

    N/A

  • Study Type

    Non-Clinical

  • Clinical Trial Details

    N/A

  • Broad Policy Alignment

    Pending

  • Age Group

    Not Applicable

  • Vulnerable Population

    Not applicable

  • Occupations of Interest

    Not applicable

Abstract

Continuous genomic surveillance in wastewater allows timely obtaining an overview of the SARS-CoV-2 virus variants currently circulating in Switzerland. This enables the detection of virus variants that carry resistance to vaccination or medications or lead to severe disease courses. In addition, their relative frequencies can be estimated. This is relevant in order to take measures early if necessary. The genomic surveillance includes: - Sequencing of SARS-CoV-2 gene fragments in wastewater samples, - Bioinformatic analysis of the raw sequence data to detect SARS-CoV-2 virus variants and their relative proportions, - Assessment of the applicability of this methodology for other respiratory viruses.