Infection during pregnancy has no effect on information processing in offspring
- Funded by Netherlands Organisation for Health Research and Development (ZonMW)
- Total publications:0 publications
Grant number: 11140012410003
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Key facts
Disease
N/AStart & end year
20252027Known Financial Commitments (USD)
$0Funder
Netherlands Organisation for Health Research and Development (ZonMW)Principal Investigator
ing L GroeninkResearch Location
NetherlandsLead Research Institution
Universiteit UtrechtResearch Priority Alignment
N/A
Research Category
Secondary impacts of disease, response & control measuresResearch Subcategory
Indirect health impactsSpecial Interest Tags
N/AStudy Type
Non-ClinicalClinical Trial Details
N/ABroad Policy Alignment
PendingAge Group
Not ApplicableVulnerable Population
Not applicableOccupations of Interest
Not applicable
Abstract
Infections during pregnancy can disrupt the normal brain development of the fetus. We simulated a viral infection during pregnancy in an animal model to investigate the long-term effects on the behavior of the offspring. In contrast to existing literature, we found no changes in information processing and social behavior of the mice after birth. The diet given to the mother had no apparent effect on the behavior or immune system of the offspring. Given the increased interest in the long-term effects of infections during pregnancy due to the Covid-19 pandemic, it is important to publish our negative results. This will allow the research community to better assess the usefulness of the animal model we used and learn more about the use of dietary interventions during pregnancy.