AREBO
- Funded by Agence nationale de recherche sur le sida et les hépatites virale [National Agency for AIDS Research] (ANRS)
- Total publications:0 publications
Grant number: ECTZ451482
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Key facts
Disease
EbolaStart & end year
20262026Known Financial Commitments (USD)
$528,750Funder
Agence nationale de recherche sur le sida et les hépatites virale [National Agency for AIDS Research] (ANRS)Principal Investigator
Eric DelaporteResearch Location
Congo (DRC)Lead Research Institution
Institut National de Recherche Biomédicale (INRB), Kinshasa Gombe, République Démocratique du CongoResearch Priority Alignment
N/A
Research Category
Pathogen: natural history, transmission and diagnosticsResearch Subcategory
DiagnosticsSpecial Interest Tags
N/AStudy Type
Non-ClinicalClinical Trial Details
N/ABroad Policy Alignment
PendingAge Group
Not ApplicableVulnerable Population
Not applicableOccupations of Interest
Not applicable
Abstract
AREBO aims to develop and strenghten the diagnostic capacities for BDBV in INRB central laboratories in Kinshasa and decentralised laboratories by implementing open PCR systems and rapidly deployable molecular assays for case identification. A reference PCR assay specific to BDBV will be developed for case confirmation in central laboratories, and validated on a sample panel available at INRB which has been confirmed by sequencing. Besides, as soon as commercial point-of-care molecular tests, such as GeneXpert or equivalent, specific to BDBV or pan-filovirus, will be available, these tests will be evaluated on the same reference panel to determine their respective sensitivity and specificity. Serological tests developed as part of this project will enable investigation of Ebola virus spread by detecting IgM and IgG specific to different Ebola viruses, including BDBV.