IMOVA : Phase IIa, randomized, open-label, parallel-group trial to evaluate the immunogenicity, safety, and tolerability of the Ervebo vaccine administered with Inmazeb in healthy adult volunteers.

  • Funded by Agence nationale de recherche sur le sida et les hépatites virale [National Agency for AIDS Research] (ANRS)
  • Total publications:0 publications

Grant number: ANRS0064s

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Key facts

  • Disease

    Ebola
  • Start & end year

    2026
    2027
  • Known Financial Commitments (USD)

    $705,000
  • Funder

    Agence nationale de recherche sur le sida et les hépatites virale [National Agency for AIDS Research] (ANRS)
  • Principal Investigator

    Marie Jaspard
  • Research Location

    Guinea
  • Lead Research Institution

    Service des maladies infectieuses et tropicale, Inserm UMR-1136 IPLESP Hôpital Saint-Antoine, Paris, France
  • Research Priority Alignment

    N/A
  • Research Category

    Vaccines research, development and implementation
  • Research Subcategory

    Phase 2 clinical trial
  • Special Interest Tags

    N/A
  • Study Type

    Clinical
  • Clinical Trial Details

    Clinical Trial, Phase II
  • Broad Policy Alignment

    Pending
  • Age Group

    Unspecified
  • Vulnerable Population

    Unspecified
  • Occupations of Interest

    Unspecified

Abstract

The ANRS0064s IMOVA project consists of the implementation of a phase IIa clinical trial to assess the impact of the effect, if any, of Inmazeb administration on neutralizing antibody responses induced by Ervebo Ebola Zaire vaccine. If an interaction is observed, this will determine the time interval required between administration of Inmazeb and the Ervebo vaccine.